Speaker: Garrett Mason, PhD student, University of Iowa 

Title: Asymptotic Reduction of Competitive Inhibitor Stimulation Model

Abstract: Terazosin is a drug undergoing clinical trials to be used for patients with Parkinson's disease. Riley et al proposed that it follows the mechanism of a competitive inhibitor stimulant. As a competitive inhibitor, it causes a new chemical reaction pathway to be preferred due to ratios of reaction rates causing an increase in the product's production. In this talk, I propose a nondimensionalization of the system that results in three time scales. The middle subscale time system retains hallmarks of the original system such as nonmonotone dose dependence with a bifurcation parameter.